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23rd April 2005 = AIDS CRITICS DAY / Letter to the Editor
by Hugo Webber Sunday April 24, 2005 at 06:33 AM

On the 23rd April 1984 at a press conference in Washington, Dr. Robert Gallo proclaimed to the world, that he had discovered HIV the probable cause for AIDS. To mark this day, many AIDS-CRITICS worldwide will make the 23rd April a DAY of ACTION and voice CRITIC about the "HIV causes AIDS" theory...

please add YOUR COMMENTS and forward to relevant newspapers...
-----------------------------------------------------------------------------------------------

23rd April 2005 = AIDS CRITICS DAY / Letter to the Editor

Dear Editor,

On the 23rd April 1984, Dr. Robert Gallo declared on a press conference in Washington, that he had discovered a Virus (HTLV-III lateron to renamed as HIV) the probable cause for AIDS.

During these 21 years gone, billions of Dollars have been spend on
scientific research to find a vaccine or a cure. So far with no adequate result.

So wouldn´t it be time perhaps to apply the same principles of
"controlling" as in any other industry? Isn't the time ripe for some
kind of rethinking with regards to the whole "HIV causes AIDS" theory?

Furtheron, there is a growing number of critical doctors, scientists and politicians to the rather onesided views that have been published about the aids pandemic.

This letter would be tooo long to go into detail on all the different aspects, that critical scientists have pointed out, but the main points of aids criticism are:

So far HIV has NOT fulfilled the "Koch postulates" (The worldwide
excepted criteria to prove that a microbe is the cause for an illness, developed over a hundred years ago by the german scientist Robert Koch)

HIV has not been isolated from other body cell material.

There is no electromagnetic photo of HIV available. What has been
published many times are either computer animations or photos from cell material with no specifics as requested by strict scientific rules.

In view of the development over the last 21 years, wouldn´t it be a
responsibility from the media to inform the general public about these concerns?

How come, that there are discussions accepted about complementary
therapies when someone has high blood pressure, a heart attack or even cancer, while the "HIV causes AIDS" theory seems to be repeated again and again almost like a religious dogma and people who question this are labelled "dissidents" "denialists" "communists" "new age thinkers" "flat earthers" or even "nazi's".

Fact of the matter is, that there are over 2000 scientists worldwide who have voiced aids critical opinions. This list includes highly acclaimed scientists and nobel price winners like Prof. Kary Mullis.

More and more people who have been diagnosed HIV+ refuse to take the so called "aids cocktails" because there are reports that these are highly toxic and resort to a healthy lifestyle combined with a mixture of natural remedies and other complementary methods.

Furtheron there are over 9000 signatures from people worldwide, who have signed the petition of truth initiated by President Thabo Mbeki from South Africa.

There are hundreds of websites where one can read some of the critical comments about HIV and AIDS.

There are millions of results, if one enters any of the aids-critics
keywords.

So my main question is: "Why are the mainstream media outlets sooo
reluctant to publish anything to do with "AIDS CRITICISM" ?

Could it be true, that the pressure from pharmaceutical companies to
reduce advertising is so much bigger, then the often resorted terms of
"democratic flow of information" "free speech" and the "freedom of
opinion" as practised with most parts of reporting about a given topic.

We, the growing number of aids-critical people worldwide will make the 23rd April 2005 the first "DAY of ACTION" and will voice our criticism about the various aspects of the "HIV causes AIDS" theory and the consequences individually and socially.

The main scientific event on the 23rd April 2005 is the 2 day seminar "EL SIDA SI SE CURA" in Peru under the medical leadership from Dr. Roberto Giraldo. Please support that event, because there will be widespread medical repercussions, at least for most of South America... Please take also into consideration, that there are not many events that have taken place as big as the one in Peru, where critical scientific opinions are voiced by TOP doctors and scientists...

Please publish something about the AIDS CRITICS DAY on 23rd April 2005.

Thanking you for your support.

Kind Regards

Hugo Webber
Information and Communications Officer
http://www.think-fitness.de / team

---------------------------------------------------
please see relevant weblinks here >>
---------------------------------------------------

23rd April 2005 = AIDS CRITICS DAY
http://www.think-fitness.de/html/23_april_2005_aids.html

What can YOU do on 23rd April = CRITICAL AIDS DAY?
http://www.think-fitness.de/html/critical_aids_day.html

Dia Critico del SIDA
http://www.laverdaddelsida.com/

Over 2000 have doctors, scientists and concerned people signed the
petition to support "The Group for the Scientific Reappraisal of the
HIV-AIDS Hypothesis"
http://www.virusmyth.net/aids/statement/

IS “HIV” REALLY THE CAUSE OF AIDS? a few hundred aids quotes
http://www.aras.ab.ca/aidsquotes.htm

Over 2000 people on the list from Alberta Reappraising Aids Society
http://www.aras.ab.ca/thelist.htm

Over 9000 people have signed the Petition to support President Thabo
Mbeki / South Africa
http://www.virusmyth.net/aids/news/mbeki.htm

More quotes and links from AIDS-Critics
http://www.think-fitness.de/html/aids_critics.html

Top 100 AIDS Science Inconsistencies
http://www.geocities.com/pharmharm/Top100.html

forums from aids critical people, to show you, that all the above is not
just plain theory, but an ever growing number of concerned people
discuss the various topics of HIV-AIDS from an alternative point of
view. When will YOU join us?

dissident action
http://www.dissidentaction.com/

aidsmythexposed
http://groups.msn.com/aidsmythexposed/messageboard.msnw

german forum
http://f23.parsimony.net/forum51884/index.htm

latino forum
http://groups.msn.com/TheLatinoForum

for further research, please enter any combination of keywords below.
You'll be surprised...

keywords: aids critics day # critical aids day # 23rd april 1984 aids # 23rd april 2005 aids # aids critics books # criticalaidsday #
aidscriticsday # aids critics # aids dissidents # aids controversy # dr gallo critics # aids lawsuits # aids court cases # azt critics # aids censorship # critical virology # aids criticism # hiv-aids censorship # aids-hiv critics # hiv critics # dr gallo lawsuits # azt toxicity # haart toxicity # interferon toxicity # dr gallo court cases # hiv test false positive # aids lies # hep-c critic # hiv-hcv critics # hiv test critic # aids war # aids keywords # robert gallo critic # critical virologists # koch postulates # aids critics keywords campaign #

add your comments


GREAT POST!!!!!!
by Vivian Stamp Sunday April 24, 2005 at 01:14 PM

GREAT POST!!!!!!...
click to enlarge

testingforum.jpg, image/jpeg, 653x536

Unreliable Tests

A September 2004, San Francisco Chronicle article considered the "beauty" of testing. It told the story of 59 year-old veteran Jim Malone, who'd been told in 1996 that he was HIV positive. His health was diagnosed as "very poor." He was classified as "permanently disabled and unable to work or participate in any stressful situation whatsoever."

In 2004, his doctor sent him a note to tell him he was actually negative. He had tested positive at one hospital, and negative at another.

Nobody asked why the second test was more accurate than the first (this was the protocol at the Veteran's Hospital). Having been falsely diagnosed and spending nearly a decade waiting, expecting to die, Malone said, "I would tell people to get not just one HIV test, but multiple tests. I would say test, test and retest."

In the article, AIDS experts assured the public that the story was "extraordinarily rare." But the medical literature differs significantly.

The Numbers

In 1985, at the beginning of HIV testing, it was known that "68% to 89% of all repeatedly reactive ELISA (HIV antibody) tests [were] likely to represent false positive results." (New England Journal of Medicine. 1985).

In 1992, the Lancet reported ("HIV Screening in Russia") that for 66 true positives, there were 30,000 false positives. And in pregnant women, "there were 8,000 false positives for 6 confirmations."

In September 2000, the Archives of Family Medicine stated that the more women we test, the greater "the proportion of false-positive and ambiguous (indeterminate) test results."

The tests described above are standard HIV tests, the kind promoted in the ads. Their technical name is ELISA or EIA (Enzyme-linked Immuno-sorbant Assay). They are antibody tests. The tests contain proteins that react with antibodies in your blood.

False Positives

In the U.S., you're tested with an ELISA first. If your blood reacts, you'll be tested again, with another ELISA. Why is the second more accurate than the first? That's just the protocol. If you have a reaction on the second ELISA, you'll be confirmed with a third antibody test, called the Western Blot. But that's here in America. In some countries, one
ELISA is all you get.

It is precisely because HIV tests are antibody tests that they produce so many false-positive results. All antibodies tend to cross-react. We produce anti-bodies all the time, in response to stress, malnutrition, illness, drug use, vaccination, foods we eat, a cut, a cold, even pregnancy. These antibodies are known to make HIV tests come up as positive.

The medical literature lists dozens of reasons for positive HIV test results: "transfusions, transplantation, or pregnancy, autoimmune disorders, malignancies, alcoholic liver disease, or for reasons that are unclear..." (Archives of Family Medicine. Sept/Oct. 2000).

"[L]iver diseases, parenteral substance abuse, hemodialysis, or vaccinations for hepatitis B, rabies, or influenza..." (Archives of Internal Medicine, August 2000).

The same is true for the confirmatory test the Western Blot. Causes of indeterminate Western Blots include: "lymphoma, multiple sclerosis, injection drug use, liver disease, or autoimmune disorders. Also, there appear to be healthy individuals with antibodies that cross-react...."
(ibid).

Pregnancy is consistently listed as a cause of positive test results, even by the test manufacturers." [False positives can be caused by] prior pregnancy, blood transfusions...and other potential nonspecific reactions." (Vironostika HIV Test, 2003).

Inflated Africa Numbers

This is significant in Africa, because HIV estimates for African nations are drawn almost exclusively from testing done on groups of pregnant women.

In Zimbabwe last year, the rate of HIV infection among young women decreased remarkably, from 32.5 to 6 percent. A drop of 81 percent overnight. UNICEF's Swaziland representative, Dr. Alan Brody, told the press that, "The problem is that all the sero-surveillance data came from pregnant women, and estimates for other demographics was based on that."
(PLUS News, August, 2004).

Flawed Samples

When these pregnant young women are tested, they're often tested for other illnesses, like syphilis, at the same time. There's no concern for cross-reactivity or false-positives in this group, and no repeat testing. One ELISA on one girl, and 32.5 percent of the population is suddenly HIV positive.

The June 20, 2004 Boston Globe reported "the current estimate of 40 million people living with the AIDS virus worldwide is inflated by 25 percent to 50 percent." It said that HIV estimates for entire countries have, for over a decade, been taken from "blood samples from pregnant women at prenatal clinics."

But numbers about "AIDS deaths, AIDS orphans, numbers of people needing antiretroviral treatment, and the average life expectancy" are all taken from that one test.

I've certainly never seen this in a VH1 ad.

At present there are about six-dozen reasons given in the literature why the tests come up positive. In fact, the medical literature states that there is simply no way of knowing if any HIV test is truly positive or negative:

"[F]alse-positive reactions have been observed with every single HIV-1 protein, recombinant or authentic." (Clinical Chemistry. 37; 1991). "Thus, it may be impossible to relate an antibody response specifically to HIV-1 infection." (Medicine International. 1988).

Ambiguous Results

And even if you believe the reaction is not a false positive, "the test does not indicate whether the person currently harbors the virus."
(Science. November, 1999).

The test manufacturers state that after the antibody reaction occurs, the tests have to be "interpreted." There is no strict or clear
definition of HIV positive or negative. There's just the antibody reaction. The reaction is colored by an enzyme, and read by a machine called a spectro-photometer.

The machine grades the reactions according to their strength (but not specificity), above and below a cut-off. If you test above the cut-off, you're positive; if you test below it, you're negative. So what determines the all-important cut-off? From The CDC's instructional material: "Establishing the cutoff value to define a positive test result from a negative one is somewhat arbitrary." (CDC, 2003)

add your comments


How the scam of AID$ in Africaworks
by Paul King Monday April 25, 2005 at 05:05 PM

The Bangui Definition

In 1985, the World Health Organization called a meeting in Bangui, the
capital of the Central African Republic, to define African AIDS. The
meeting was presided over by CDC official Joseph McCormick. He wrote
about it in his book "Level 4 Virus Hunters of the CDC," saying, "If I
could get everyone at the WHO meeting in Bangui to agree on a single,
simple definition of what an AIDS case was in Africa, then, imperfect as
the
definition might be, we could actually start counting the cases..." The
result was that African AIDS would be defined by physical symptoms:
fever, diarrhea, weight loss and coughing or itching. ("AIDS in Africa: an

epidemiological paradigm." Science, 1986).

In Sub-Saharan Africa, about 60 percent of the population lives and
dies without safe drinking water, adequate food or basic sanitation. A
September, 2003 report in the Ugandan Daily "New Vision" outlined the
situation in Kampala, a city of approximately 1.3 million inhabitants,
which, like most tropical countries, experiences seasonal flooding. The
report describes "heaps of unclaimed garbage" among the crowded houses in

the flood zones and "countless pools of water [that] provide a breeding
ground for mosquitoes and create a dirty environment that favors
cholera."

"Latrines are built above water streams. During rains the area
residents usually open a hole to release feces from the latrines. The rain
then
washes away the feces to streams, from where the [area residents] fetch
water. However, not many people have access to toilet facilities. Some
defecate in polythene bags, which they throw into the stream." They
call these, "flying toilets."

The state-run Ugandan National Water and Sewerage Corporation states
that currently 55 percent of Kampala is provided with treated water, and
only 8 percent with sewage reclamation.

Most rural villages are without any sanitary water source. People wash
clothes, bathe and dump untreated waste up and down stream from where
water is drawn. Watering holes are shared with animal populations, which
drink, bathe, urinate and defecate at the water source. Unmanaged human
waste pollutes water with infectious and often deadly bacteria.
Stagnant water breeds mosquitoes, which bring malaria. Infectious
diarrhea,
dysentery, cholera, TB, malaria and famine are the top killer in Africa.
But in 1985, these conditions defined AIDS.

add your comments


AIDS CRITICS DAY - HIDDEN
by Keith Styles Monday April 25, 2005 at 06:42 PM
huntsman.ks@gmail.com

The science of HIV, AIDS and the proposition that HIV=AIDS is long overdue for real scientific investigation and a frank and open debate. It is not happening. WHY?
All discussion related to these issues is done on the premise that HIV is an established fact. That proposition is simple not true!
This is a great post. I'm concerned the editors have seen fit ot HIDE it!

add your comments


more aids-critical discussions
by Hugo Webber Tuesday April 26, 2005 at 01:18 AM

Dear Reader,

You may be new to the aids-critical discussion, or perhaps you have come to your own conclusions already. At any rate, since there are so many scientific questions, which are subject to questioning, please add YOUR COMMENTS to any of the ongoing threads worldwide...

With best wishes
Hugo Webber

For more info see here >>
23rd April = AIDS CRITICS DAY
http://www.think-fitness.de/html/23_april_2005_aids.html

Portland Indymedia
Anniversary of a Medical Tragedy
Http://portland.indymedia.org/en/2005/04/316077.shtml

San Diego Indymedia
Anniversary of a Medical Tragedy
http://sandiego.indymedia.org/en/2005/04/108470.shtml

Irish Indymedia
Why Bono and HIV/AIDS Inc will be stopped
http://www.indymedia.ie/newswire.php?story_id=68548

Bristol Indymedia / UK
23rd April 2005 = AIDS CRITICS DAY / Letter to the Editor
http://bristol.indymedia.org/newswire/display/22509/index.php

Sydney Indymedia / Australia
23rd April 2005 = AIDS CRITICS DAY / Letter to the Editor
Http://sydney.indymedia.org/front.php3?article_id=54573&group=webcast

Perth Indymedia / Australia
23rd April 2005 = AIDS CRITICS DAY / Letter to the Editor
Http://perth.indymedia.org/index.php?action=newswire&parentview=10037

India Indymedia
23rd April 2005 = AIDS CRITICS DAY / Letter to the Editor
Http://india.indymedia.org/en/2005/04/210434.shtml

South Africa Indymedia
23rd April 2005 = AIDS CRITICS DAY / Letter to the Editor
http://southafrica.indymedia.org/news/2005/04/8033.php

Austria Indymedia
23rd April 2005 = AIDS CRITICS DAY
http://at.indymedia.org/mod/otherpress/display/2282/index.php
(many people speak english there, so even if this is a german language board, add your comments.)

German dissident forum
http://f23.parsimony.net/forum51884/
(not very active, shows that the number of aids-critical people in germany is not all that big. could do with some fresh input. Needs registration, but the moderator speaks english)

To search, use any combination of aids-critical keywords >>
aids critics # aids controversy # dr gallo critics # azt critics # aids critics books # aids lawsuits # aids court cases # aids censorship # critical virology # hiv aids censorship # hiv-aidsaids critics # aids dissidetns # hiv critics # dr gallo lawsuits # azt toxicity # haart toxicity # interferon toxicity # dr gallo court case(s) # hiv test false positive # aids lies # hep-c critics # hiv-hcv critics # hiv test critics # aids war # aids keywords # robert gallo critics # critical virologists # koch postulates # aids critics keywords campaign #

Aids Critics Keywords Campaign >>
http://www.think-fitness.de/html/aids_keywords.html

add your comments


WHY HIDDEN ?
by Mark Twain II Tuesday April 26, 2005 at 06:43 AM

The fact, that even on an indymedia FREE PUBLISHING site, it is not possible to openly discuss the various aspects about HIV-AIDSshows how deeply the aids myth has been established in the minds of people worldwide.

One could only hope, that the editotial board took a closer look into the substance of aids-critisism and not only allow, but actually foster these discussions...

lives would be saved!!!

add your comments


Editorial Note
by h-indymedia Tuesday April 26, 2005 at 07:28 PM

just to clarify, the original story was only hidden because it was posted twice to the newswire. As people have posted comments to this version we have now hidden the other duplicate instead

MIM collective

add your comments


HIV-AIDS RADIO & VIDEO
by Hugo Webber Saturday April 30, 2005 at 07:33 AM

Hi all,

Let me say a BIG THANK YOU to the editorial board here in Melbourne for the publication. Tec problems can always occur, so that is not an issue...

The various messages in this and other threads worldwide show, that there are many, many people concerned about the TRUTH with regard to HIV-AIDS and other medical topics. It will take some time to digest all the information, but i surely will come back again and again to read and check the various links.

Here are two more about aidscritical RADIO and VIDEO documentaries.

AIDS CRITICS RADIO
http://www.think-fitness.de/html/aids_critics_radio.html

AIDS CRITICS VIDEO
http://www.think-fitness.de/html/aids_critics_videos.html

ORGANIZE A HEALTH-INFOTAINMENT PARTY...

With these radio- and videolinks, respectively the INTERVIEWS and VIDEO CLIPS, you have enough material to organize a small HEALTH-INFOTAINMENT PARTY. Pass the radio- and video links onto your friends...

If you haven't got the technical resources, consider that many people have the latest tec-features because they like playing games on the net, listen to music, watch videos or are even active artists or musicians.

So ask a friend or a "friend of a friend" if they would help with such a HEALTH-INFOTAINMENT PARTY. Start small, even 5-10 people initially will be enough to get the discussion started "IS HIV really the cause for AIDS?"

Try to get in touch with musicians, artists, journalists, students, health-care- and social workers, political activists and help spreading the word: "THERE ARE MANY OPEN SCIENTIFIC QUESTIONS about HIV-AIDS"

Keep raising the question : "WHY DO MOST MAINSTREAM MEDIA OUTLETS ONLY PUBLISH ONE SIDE OF THE SCIENTIFIC DEBATE?"

Be persistent!!! The 23rd April 2005 was NOT intended as an ONE DAY ACTION but may be understood as the beginning of an ever increasing CAMPAIGN FOR TRUTH about "hiv-aids"

There are plenty of recourses on the internet, but we, the aids-critical activists have to be more outgoing into general forums and other available internet platforms, so that more and more people become aware of the "AIDS CONTROVERSY"

ACTION IS WHAT MATTERS !!!

Kind Regards
Hugo webber
http://www.think-fitness.de

ps: if anyone should know of more RADIO or VIDEO links, please post here

Please enter some of these or similar keywords into a searchengine:

aids keywords # aids critics radio # aids critics videos # 23 April 1984 aids # aids critics # 23rd April 2005 aids # aids controversy # aids critics day # critical aids day # dr gallo critics # azt critics # aids lawsuits # aids court cases # aids censorship # aids critics books # critical virology # hiv-aids censorship # aids dissidents # hiv-aids critic # dr gallo lawsuits # azt toxicity # haart toxicity # interferon toxicity # dr gallo court cases # hiv test false-positive # elisa test critics # aids lies # hep-c critic(s) # hiv-hcv critics # hiv test critics # aids war # robert gallo critics # critical virologists # retroviruses definition # durban declaration # aids critics forum # aids critics keywords campaign # koch postulates #

...add your own keywords or keyword-combination as suitable ...you will be surprised !!

add your comments


AIDS: the Fabricated Epidemic
by Johnson Monday May 02, 2005 at 11:02 AM

over 80 comments on this fast moving aids debate already... join in!!

AIDS: the Fabricated Epidemic

http://www.freerepublic.com/focus/news/1394741/posts?q=1&&page=1#1

add your comments


"But you don't look sick!" - snapshot of a man with HIV/AIDS
by Dennis Wednesday May 04, 2005 at 03:36 AM

there are two very controversial aids disccusions going on here. add your comments...

http://perth.indymedia.org/?action=newswire&parentview=10181

http://perth.indymedia.org/index.php?action=newswire&parentview=10037

add your comments


'MEDS' not 'HIV' - The real killer
by DAG Wednesday May 04, 2005 at 07:55 AM

'MEDS' not 'HIV' - T...
aztlabel.jpg, image/jpeg, 450x172

'MEDS' not 'HIV' - The real killer
Don't believe what the drugs companies tell you.

WITHOUT HAART 'MEDS"

“These long-term nonprogressors [Hiv+ people who remained healthy] are a heterogeneous group with respect to viral load and HIV-1 responses…none had been treated with antiretroviral agents.”

AIDS Research and Human Retroviruses, 12: 585 (1996)
– Harrer, Thomas, et al, Aids Researchers

NOT ONE USED HAART

“Subjects: homosexual men in Amsterdam. “None of the LTAs [long-term asymptomatics–people who remained healthy]…received any antiviral drugs during the study [7 years].”

“Ten HIV+ people; 11-15 years infected; non-progressors [i.e., healthy]; maintained stable T-cell counts above 500. “These long-term nonprogressors…all showed the same risk factor (sexual exposure), and all had...virus...and none had been treated with antiretroviral agents.”

AIDS Research and Human Retroviruses, 12: 585 (1996)
– Harrer, Thomas, et al, Aids Researchers
Journal of Infectious Diseases, 171:811 (1995)
– Hogervorst E, et al, Aids Researchers
_________
__________

WITH HAART

“…Choosing between many of these [HAART] combinations is, therefore, increasingly dependent upon knowledge of antiretroviral toxicities...[which include] myopathy [gross muscle atrophy] (zidovudine [AZT]), neuropathy (stavudine, didanosine, zalcitabine; hepatic steatosis and lactic acidaemia (didanosine, stavudine, zidovudine); and possible also peripheral lipoatrophy and pancreatitis (didanosine)...drug hypersensitivity... lipodystrophy...[including] peripheral fat loss (Presumed lipoatrophy in the face, limbs and buttocks) and central fat accumulation (within the abdomen, breasts and over the dorsocervical spine [so-called buffalo hump]...[and prevalent in] about 50% [of patients] after 12-18 months of therapy...Metabolic features significantly associated with lipodystrophy and protease-inhibitor therapy include hypertriglyceridaemia, hypercholesterolaemia, insulin resistance...and type 2 ...diabetes mellitus. Dyslipidaemia at concentrations associated with increased cardiovascular disease occurs in about 70% of patients. These metabolic abnormalities are more profound in those receiving protease inhibitors...Most cases of diabetes have been identified in recipients of protease inhibitors...Anemia and granulocytopenia affect about 5-10% of patients who receive zidovudine...Virtually all antiretroviral medications can cause nausea, vomiting, or diarrhoea early in therapy...Diarrhea is probably most common with protease inhibitors...Most antiretroviral agents have been associated with hepatic [liver] toxicity...Most protease inhibitors seem to result in increased rates of spontaneous bleeding (bruising, haemarthrosis, and rarely intracranial haemorrhage) in haemophiliacs... 25-35% of patients cannot tolerate [AZT monotherapy] or triple combination therapy for 4 weeks...”

Lancet. 2000 Oct 21;356:1423-0.
– Carr A, Cooper DA, Aids Researchers

BLINDNESS

“This study was conducted to determine the likelihood of the development of [immune recovery vitritis, IRV], which causes vision loss in AIDS patients with cytomegalovirus (CMV) retinitis, who respond to HAART. We followed 30 HAART-responders…Symptomatic IRV developed in 19 (63%) of 30 patients.”

J Infect Dis. 1999 Mar;179(3):697-700

CASTLEMAN'S DISEASE

“Recently, we observed an unusual cluster of cases of rapidly progressing multicentric Castleman’s disease. Fever, weakness, generalized enlargement of lymph nodes, and marked polyclonal gammopathy developed in three patients with AIDS...Two of these patients died within one week after the diagnosis, with generalized involvement of the lymphatic system, liver, and bone marrow at autopsy. A fourth patient with AIDS who died equally rapidly after the diagnosis of multicentric Castleman’s disease had been seen in our hospital 14 months earlier... symptoms…started after the initiation of highly active antiretroviral therapy in these three patients.”

N Engl J Med. 1999 Jun 17;340(24):1923-4
– Zietz C, et al, Aids Researchers
– Karavellas MP, et al, Aids Researchers

DEATH
“…Of the 70 patients studied, 84% were still alive after the 3-month study period...17 surviving patients (24%) had HAART regimens discontinued due to drug intolerance and 11 (16%) expired [died] during the study period...”
J Pain Symptom Manage. 2001 Jan;21(1):41-51

NERVE DAMAGE

“The antiretroviral drugs currently licensed in the United Kingdom [June 1996] are zidovudine (azidothymidine [AZT]), zalcitabine (ddC) and didanosine (ddI). All three are nucleoside analogues...All are very toxic. Suppression of bone marrow elements can occur with any of the three, as can peripheral neuropathy [nerve damage].”

Adverse Drug Reaction Bulletin. 1996 Jun;178:675-8.
– Ellis C.J., Leung D., Aids researchers

“A decrease in mtDNA [DNA of the mitochondria; the energy regulating entities within every cell] content was found in HAART-treated HIV-infected patients with peripheral fat wasting in comparison with subjects in the control cohorts...Lipodystrophy with peripheral fat wasting following treatment with NRTI [Nucleoside Reverse Transcriptase Inhibitor]-containing HAART is associated with a decrease in subcutaneous adipose [under the skin fat] tissue.”

AIDS. 2001;15:1801-9
– Shikuma CM, Hu N, Milne C, et al, Aids Researchers

‘These drugs are as dangerous as chemotherapy,’
“7 HIV patients presenting LD [Lipodystrophy, all taking antiretroviral therapy] and 5 HIV non-LD controls participated in the study…Structural muscle abnormalities, mitochondrial respiratory chain dysfunction or mtDNA deletions were detected in all HIV lipodystrophic patients. The mitochondrial abnormalities found suggest that mitochondrial dysfunction could play a role in the development of antiretroviral therapy-related lipodystrophy. ”
AIDS. 2001 Sep 7;15(13):1643-51
– Zaera MG, et al, Aids Researchers

“Combination drug therapy, or the triple-drug ‘cocktail’…often provokes severe side effects… ‘These drugs are as dangerous as chemotherapy,’ warned Dr. James Kahn, UCSF associate professor of medicine…”
– Science Daily, Sep 4, 2001

SEXUAL DIFFICULTIES - Body distortions

“[Chapters in this guide to HIV drugs are entitled Introduction, Appetite loss, Body distortions (lipodystrophy), Bone death and destruction, Cardiac concerns, Diarrhea, Fatigue, Gas and bloating, Hair loss, Headaches, Insulin resistance and diabetes, Kidney stones, Liver toxicity, Muscle aches and pains, Nausea and vomiting, Nightmares, daymares and sleeping difficulties, Pancreatitis, Peripheral neuropathy, Skin problems, Sexual difficulties, The end]”

– A Practical Guide to HIV Drug Side Effects, CATIE, 2002

HEART ATTACKS
“Use of protease inhibitors was strongly associated with the likelihood of having a myocardial infarction [heart attack] and correlated with diabetes mellitus and hyperlipidaemia.”
Lancet. 2002 Nov 30;360(9347)
– Holmberg SD, et al, Aids Researchers

add your comments


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